Use the lancet to prick your finger and collect a drop of blood.
INSTI Multiplex HIV-1 / HIV-2 Syphilis Antibody Test
One sample. One minute. Two results.
The INSTI Multiplex Antibody Test screens for HIV-1, HIV-2, and syphilis simultaneously from a single fingerstick blood sample, delivering both results in as little as 60 seconds. Built on the proven INSTI flow-through platform, it gives healthcare professionals a fast, reliable way to detect co-infections in one streamlined workflow.
Designed for trained personnel in clinical, laboratory, and community outreach settings. No external timers or additional equipment required.
Access technical documentation for the INSTI Multiplex HIV-1/HIV-2/Syphilis Antibody Test.
Instructions for Use (IFU)
Complete testing procedure for multiplex screening, result interpretation (three-dot format), safety information, and storage guidelines.
Download IFU (PDF)
Product Data Sheet
Technical specifications, performance data, and ordering information for the multiplex assay.
Download Data Sheet (PDF)
Training Resources
Video demonstrations and training materials for healthcare professionals, available through INSTI University.
Visit INSTI UniversityScreen for HIV and Syphilis in a Single Test
HIV and syphilis co-infection is a growing global health concern. The two infections share common transmission routes, and the presence of syphilis can increase both the risk of acquiring HIV and the likelihood of transmitting it. In populations where one infection is prevalent, the other is often close behind.
Traditional screening protocols require separate tests for each infection, doubling the time, supplies, and steps involved. The INSTI Multiplex changes that. One fingerstick, one test device, one minute. Both results appear on the same membrane unit, clearly differentiated by distinct dot positions.
For healthcare providers, this means faster throughput in high-volume settings, reduced supply costs, and fewer opportunities for patients to leave before receiving results. For public health programs, it means more comprehensive screening with less complexity.
Why multiplex testing matters:
Detects HIV-1 antibodies, HIV-2 antibodies, and antibodies directed against Treponema pallidum (syphilis) antigens from one sample. Eliminates the need for separate HIV and syphilis rapid tests. Reduces per-patient testing time and consumable costs. Supports prenatal screening, sexual health programs, and outreach settings where co-infection risk is elevated. Minimizes lost-to-follow-up by delivering both results before the patient leaves.
Product Specifications
Everything you need to evaluate INSTI for your testing program, at a glance.
| Specification | Details |
|---|---|
| Test Name | INSTI Multiplex HIV-1/HIV-2 Syphilis Antibody Test |
| Test Type | Rapid, visually read flow-through immunoassay |
| Intended Use | Simultaneous qualitative detection of antibodies to HIV-1, HIV-2, and Treponema pallidum (syphilis) |
| Specimen Types | Fingerstick whole blood, venous whole blood, plasma, serum |
| Time to Result | As little as 60 seconds |
| HIV Sensitivity | 99.3–100% (fingerstick blood) |
| HIV Specificity | 99.0–99.8% (fingerstick blood) |
| Syphilis Detection | >Measures antibodies directed against T. pallidum antigens |
| Antibodies Detected | IgM and IgG (enables earlier detection) |
| Control | Built-in IgG capture procedural control |
| Results Format | Three distinct dot positions on one membrane: control, HIV, syphilis |
| Storage | 2–30°C. Do not freeze. Store in original packaging. |
| Shelf Life | Refer to expiration date on packaging |
| Kit Contents | Membrane unit, sample diluent, color developer, clarifying solution, lancet, pipette, alcohol swab |
| Regulatory Approvals | CE Marked (EU), Health Canada Approved, Australia ARTG Listed |
| Packaging | Available in point-of-care use packaging |
Proven in Clinical and Public Health Settings
The INSTI Multiplex HIV-1/HIV-2 Syphilis Antibody Test has been available since 2015, building on the same platform that powers over 15 million INSTI tests worldwide.
It is approved and recognized by leading regulatory bodies:
Used by sexual health clinics, prenatal care programs, harm reduction organizations, and community health initiatives across multiple countries. The multiplex format is particularly valued in settings where co-infection screening is part of standard protocol.
THREE STEPS. ONE MINUTE. DONE.
Testing yourself for HIV has never been simpler. Here's exactly how it works:
Add your blood into Bottle 1 and shake.
ADD BLOOD SAMPLE
Shake and pour solutions one at a time.
POUR SOLUTIONS
What Healthcare Professionals Say
Simplify Your Co-Infection Screening
One test that screens for both HIV and syphilis in 60 seconds. Whether you're running a sexual health clinic, a prenatal screening program, or a community outreach initiative, the INSTI Multiplex can help you do more with less. Get in touch to discuss pricing, volume orders, and implementation.
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